Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440518 | 0.95 | SSTR1 (0.51) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL19276735 | 0.91 | SSTR1 (0.48) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL19276742 | 0.91 | SSTR1 (0.48) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL17087680 | 0.91 | SSTR1 (0.45) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL17471464 | 0.90 | PTPN1 (0.44) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL12468845 | 0.90 | PTPN1 (0.44) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL13415641 | 0.90 | PTPN1 (0.44) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL11985212 | 0.88 | PTPN1 (0.48) | PTPN1PTPN2PTPN6PTPN11MEN1 | |
| SCHEMBL15870687 | 0.87 | PTPN1 (0.44) | PTPN1PTPN2PTPN6PTPN11SSTR1 | |
| SCHEMBL8573455 | 0.86 | PTPN1 (0.47) | PTPN1PTPN2PTPN6PTPN11SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348414-A1 | NOVEL SYNTHETIC ANTICANCER, ANTIFUNGAL, AND ANTIBACTERIAL VACCINES | WAYNE STATE UNIVERSITY (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348414-A1 | NOVEL SYNTHETIC ANTICANCER, ANTIFUNGAL, AND ANTIBACTERIAL VACCINES | ERG28, DDOST, STT3A | PTPN1 1915/4885PTPN2 1924/4885PTPN6 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.