Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.84 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785285 | 0.91 | KLKB1 (1.00) | KLKB1 | |
| SCHEMBL17785338 | 0.88 | KLKB1 (0.94) | KLKB1F11 | |
| SCHEMBL28379609 | 0.85 | KLKB1 (0.78) | KLKB1F11 | |
| SCHEMBL24176220 | 0.81 | KLKB1 (0.83) | KLKB1 | |
| SCHEMBL21081704 | 0.80 | KLKB1 (0.70) | KLKB1F11 | |
| SCHEMBL17785314 | 0.76 | KLKB1 (0.65) | KLKB1F11 | |
| SCHEMBL31339410 | 0.75 | KLKB1 (0.63) | KLKB1F11 | |
| SCHEMBL17785263 | 0.75 | KLKB1 (0.63) | KLKB1F11 | |
| SCHEMBL17786836 | 0.71 | KLKB1 (0.67) | KLKB1F11 | |
| SCHEMBL17785303 | 0.71 | KLKB1 (0.58) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207983-A1 | PYRAZOLE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2017-12-07 | — | — | WO | disclosed |