Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683281 | 0.89 | AURKA (0.32) | AURKACYP3A4HPGDKDM4EALDH1A1 | |
| SCHEMBL19683285 | 0.88 | CYP1A1 (0.31) | AURKACYP3A4HPGDCYP1A1CYP1A2 | |
| SCHEMBL19683427 | 0.85 | AURKA (0.33) | AURKACYP3A4HPGDKDM4EALDH1A1 | |
| SCHEMBL19683514 | 0.83 | — | — | |
| SCHEMBL19683276 | 0.81 | CYP3A4 (0.33) | AURKACYP3A4HPGDCYP1A1CYP1A2 | |
| SCHEMBL19683284 | 0.80 | CYP3A4 (0.32) | CYP3A4HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL19683504 | 0.79 | — | — | |
| SCHEMBL19683509 | 0.78 | MAOA (0.42) | CYP3A4HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL19683520 | 0.78 | — | — | |
| SCHEMBL19683510 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10935552-B2 | Aie luminogens for visualization and treatment of cancer | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-03-02 | — | — | US | disclosed |
| US-20180156811-A1 | AIE LUMINOGENS FOR VISUALIZATION AND TREATMENT OF CANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-06-07 | — | — | US | disclosed |
| US-20180156811-A1 | AIE LUMINOGENS FOR VISUALIZATION AND TREATMENT OF CANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-06-07 | — | — | US | disclosed |
| WO-2017210072-A1 | ELECTROACTIVE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10935552-B2 | Aie luminogens for visualization and treatment of cancer | LAMP1, LAMP2, BECN1 | AURKA 88/4885CYP3A4 1174/4885HPGD 2729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.