SCHEMBL19683290

SCHEMBL19683290

c1ccc2c(c1)c1[nH]ccc1c1cc[nH]c21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
CCR8 P51685 1/20 0.43
KMT2A Q03164 1/20 0.42
HTR6 P50406 2/20 0.40
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39
BLM P54132 1/20 0.39
PARP15 Q460N3 1/20 0.39
RECQL P46063 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AHR P35869 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2822133 0.97 MAOA (0.42) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL29532306 0.97 MAOA (0.42) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL15985576 0.94 MAOA (0.41) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL12270273 0.89 MAOA (0.43) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL22048783 0.84 MAOA (0.44) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL12270292 0.84 MAOA (0.44) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL12219425 0.83 CCR8 (0.52) PARP1MAOAMAOBCCR8KMT2A
SCHEMBL12219421 0.82 CCR8 (0.50) PARP1CCR8KMT2AKDM4EHSD17B10
SCHEMBL2559892 0.76 PARP1 (0.43) PARP1ALDH1A1LMNA
SCHEMBL2552450 0.76 KDM4E (0.59) PARP1KMT2AKDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 WO disclosed