SCHEMBL19683541

SCHEMBL19683541

Brc1cc2ccc3c(ccc4cc(Br)oc43)c2o1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.34
ESR2 Q92731 6/20 0.33
ESR1 P03372 5/20 0.31
GPR35 Q9HC97 2/20 0.31
CYP3A4 P08684 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
PKLR P30613 1/20 0.31
GALNT2 Q10471 1/20 0.31
GALNT1 Q10472 1/20 0.31
GALNT3 Q14435 1/20 0.31
GALNT10 Q86SR1 1/20 0.31
GALNT13 Q8IUC8 1/20 0.31
GALNT6 Q8NCL4 1/20 0.31
GALNT14 Q96FL9 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13561957 0.83 ALDH1A1 (0.41) ALDH1A1LMNAHPGDCYP1A1CYP1A2
SCHEMBL19683385 0.73 PIM1 (0.40) CSNK2A1GPR35
SCHEMBL19683576 0.70 MAOB (0.60) ESR2ESR1CYP3A4ALDH1A1HPGD
SCHEMBL15851174 0.70 ALDH1A1 (0.41) ESR2ESR1CYP3A4ALDH1A1HPGD
SCHEMBL12278519 0.68 HPRT1 (0.34) CSNK2A1ESR2ESR1GPR35ALDH1A1
SCHEMBL12279379 0.68 ALDH1A1 (0.40) ESR2ESR1CYP3A4ALDH1A1HPGD
SCHEMBL18133619 0.68 ALDH1A1 (0.40) ESR2ESR1CYP3A4ALDH1A1HPGD
SCHEMBL12278759 0.65 ESR2 (0.32) ESR2ESR1CYP3A4ALDH1A1LMNA
SCHEMBL12320908 0.64 MAPT (0.51) CSNK2A1ALDH1A1LMNAHPGDPKLR
SCHEMBL12278587 0.64 KDM4E (0.39) ESR2ESR1CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114940681-A Electroactive compounds 株式会社LG化学 2022-08-26 CN disclosed
CN-110023319-B Electroactive compounds 株式会社LG化学 2022-06-17 CN disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 CN disclosed
WO-2017210072-A1 ELECTROACTIVE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-12-07 WO disclosed