Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20878943 | 0.84 | HPGD (0.44) | KDM4EHPGDBTKMAP4K4 | |
| SCHEMBL19683825 | 0.82 | NPC1 (0.44) | ALDH1A1SMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL20878933 | 0.80 | TYK2 (0.41) | MAPT | |
| SCHEMBL19683782 | 0.79 | EGFR (0.45) | ALDH1A1SMN1; SMN2KDM4EAURKA | |
| SCHEMBL19683752 | 0.79 | PLK4 (0.38) | ALDH1A1HSD17B10TTBK1TTBK2 | |
| SCHEMBL20878945 | 0.79 | EIF2AK2 (0.42) | MAPTNPC1RAB9A | |
| SCHEMBL20878968 | 0.79 | SRC (0.44) | BTKAURKA | |
| SCHEMBL23047341 | 0.76 | PRMT1 (0.42) | ALDH1A1TTBK1TTBK2BTKMAP4K4 | |
| SCHEMBL20878986 | 0.76 | EGFR (0.47) | ALDH1A1MAPTKDM4EBTKKCNH2 | |
| SCHEMBL23047328 | 0.74 | EGFR (0.44) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |