Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20878945 | 0.89 | EIF2AK2 (0.42) | SYKCDK4 | |
| SCHEMBL20878981 | 0.87 | PLK4 (0.39) | PLK4SYKPRMT1TTBK1TTBK2 | |
| SCHEMBL23047341 | 0.81 | PRMT1 (0.42) | PRMT1TTBK1TTBK2ALDH1A1 | |
| SCHEMBL20878943 | 0.80 | HPGD (0.44) | PLK4SYK | |
| SCHEMBL19683825 | 0.79 | NPC1 (0.44) | PLK4SYKALDH1A1TSHR | |
| SCHEMBL19683745 | 0.79 | ALDH1A1 (0.41) | TTBK1TTBK2ALDH1A1HSD17B10 | |
| SCHEMBL20878933 | 0.79 | TYK2 (0.41) | PRMT1 | |
| SCHEMBL23047328 | 0.78 | EGFR (0.44) | PRMT1TTBK1TTBK2KDM1AUSP2 | |
| SCHEMBL23047342 | 0.78 | PRMT1 (0.41) | SYKPRMT1TTBK1TTBK2MKNK2 | |
| SCHEMBL20878857 | 0.78 | PRMT1 (0.41) | PRMT1TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017206962-A1 | NOVEL INHIBITOR FOR FLT3 KINASE AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-12-07 | — | — | WO | disclosed |