⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827018 | 0.88 | — | — | |
| SCHEMBL649665 | 0.85 | — | — | |
| SCHEMBL11042347 | 0.85 | — | — | |
| SCHEMBL28212968 | 0.83 | CA1 (0.38) | — | |
| SCHEMBL11880025 | 0.83 | — | — | |
| SCHEMBL3058579 | 0.83 | — | — | |
| SCHEMBL4931056 | 0.81 | — | — | |
| SCHEMBL11880037 | 0.81 | — | — | |
| SCHEMBL3065332 | 0.81 | — | — | |
| SCHEMBL7355293 | 0.79 | ALOX15 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040912-B | Compounds for the treatment of kinase dependent disorders | 埃克塞里艾克西斯公司 | 2024-10-25 | — | — | CN | claimed |
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | claimed |
| WO-2021126995-A1 | METHODS AND COMPOSITIONS FOR TREATING CANCER | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2021-06-24 | — | — | WO | claimed |
| CN-108586287-A | A kind of preparation method of 2- phenyl -2- cyano butyramides | 精华制药集团南通有限公司 | 2018-09-28 | — | — | CN | claimed |
| EP-3299369-A1 | PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-03-28 | — | — | EP | claimed |
| EP-2409704-B1 | c-Met modulators and methods of use | EXELIXIS INC (US) | 2017-09-20 | — | — | EP | claimed |
| EP-1539699-A1 | 4- 7'-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004005260-A1 | A-`7-HALO-2-QUINO (XA-) LINYLOXY!PHENOXY-PROPIONIC ACID DERIVATIVES AS ANTINEOPLASTIC AGENTS | WAYNE STATE UNIVERSITY (US) | 2004-01-15 | — | — | WO | claimed |
| WO-2004004651-A2 | THERAPEUTIC AMIDES | WAYNE STATE UNIVERSITY (US) | 2004-01-15 | — | — | WO | claimed |
| US-12435061-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2025-10-07 | — | — | US | disclosed |
| EP-4574822-A2 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | Kamari Pharma Ltd. (IL) | 2025-06-25 | — | — | EP | disclosed |
| CN-118702672-A | Compounds and compositions for treating skin disorders | 卡玛瑞制药有限公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-4392035-A1 | STING MODULATORS, COMPOSITIONS, AND METHODS OF USE | University of South Florida (US) | 2024-07-03 | — | — | EP | disclosed |
| CN-115335050-B | Compounds and compositions for treating skin disorders | 卡玛瑞制药有限公司 | 2024-05-17 | — | — | CN | disclosed |
| WO-1994003428-A1 | METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE | SEPRACOR, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5258517-A | Method of preparing optically pure precursors of paroxetine | SEPRACOR, INC. (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0469550-A2 | A thermally curable mixture | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-02-05 | — | — | EP | disclosed |
| EP-0190496-A2 | Piperidine derivatives having a gastro-intestinal activity | BEECHAM GROUP PLC (GB) | 1986-08-13 | — | — | EP | disclosed |
| EP-0012112-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1983-10-05 | — | — | EP | disclosed |
| US-4291901-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |