Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175768 | 0.94 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL15227382 | 0.94 | NPC1 (0.43) | NPC1RAB9A | |
| SCHEMBL11217430 | 0.91 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL405336 | 0.85 | — | — | |
| SCHEMBL14400918 | 0.85 | — | — | |
| SCHEMBL255183 | 0.85 | — | — | |
| SCHEMBL12837824 | 0.85 | — | — | |
| SCHEMBL12837592 | 0.82 | PDE4A (0.44) | — | |
| SCHEMBL15228205 | 0.81 | PPARG (0.51) | — | |
| SCHEMBL15227915 | 0.81 | PPARG (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349544-A1 | Ethynylbenzene Derivatives | DUKE UNIVERSITY | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349544-A1 | Ethynylbenzene Derivatives | Q6ZSR9, EPX, ZYX | NPC1 2783/4885RAB9A 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.