Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FABP6 | P51161 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684895 | 0.86 | FABP6 (0.35) | FABP6PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL32691311 | 0.82 | FABP6 (0.38) | FABP6SMN1; SMN2GAAMAPTTP53 | |
| SCHEMBL19667307 | 0.79 | GRM5 (0.42) | PTPN1SMN1; SMN2MAOBNPSR1KDM4E | |
| SCHEMBL19684924 | 0.79 | PARP10 (0.41) | CNR2PTPN1PDE4DPDE4BPDE4A | |
| SCHEMBL19679348 | 0.74 | FABP6 (0.41) | FABP6LMNAGAAMAPTTSHR | |
| SCHEMBL16535556 | 0.72 | FABP6 (0.48) | FABP6LMNAGAAMAPTKDM4E | |
| SCHEMBL19684746 | 0.70 | CNR2 (0.34) | CNR2PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL5393397 | 0.69 | CYP3A4 (0.47) | CNR2LMNASMN1; SMN2MAPTMAOB | |
| SCHEMBL21593493 | 0.66 | PARP10 (0.44) | PDE4ALMNASMN1; SMN2GAAMAPT | |
| SCHEMBL19684894 | 0.65 | GRM5 (0.43) | SMN1; SMN2MAOBNPSR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348313-A1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | DUT, NCL, TYMP | CNR2 4127/4885PTPN1 4606/4885FABP6 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.