SCHEMBL1968523

SCHEMBL1968523

c1cn(CN2CCCCC2)nn1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.37
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HRH3 Q9Y5N1 2/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3897536 0.98 CYP19A1 (0.38) CYP19A1HRH3FOLH1
SCHEMBL8696853 0.82 CYP1A2 (0.39) CYP19A1CYP1A2CYP3A4HRH3
Hydrochloric Acid SCHEMBL12469489 0.81 CYP2D6 (0.34) CYP19A1HRH3
SCHEMBL10600899 0.80 CYP2D6 (0.38) CYP19A1HRH3
SCHEMBL4417504 0.80 CYP19A1 (0.35) CYP19A1CYP3A4HRH3
SCHEMBL10424811 0.77 CYP19A1 (0.48) CYP19A1FOLH1
SCHEMBL3239300 0.73 CYP19A1 (0.33) CYP19A1
SCHEMBL2296855 0.72 CYP19A1 (0.35) CYP19A1FOLH1
SCHEMBL3232529 0.69 CYP19A1 (0.49) CYP19A1CYP1A2
SCHEMBL18037556 0.68 PKM (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0160620-B1 METAL DEACTIVATORS CIBA-GEIGY AG (CH) 1989-09-13 EP claimed
EP-1879873-B1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2013-10-09 EP disclosed
EP-2334771-A1 LOW SULFUR AND LOW METAL ADDITIVE FORMULATIONS FOR HIGH PERFORMANCE INDUSTRIAL OILS ExxonMobil Research and Engineering Company (US) 2011-06-22 EP disclosed
WO-2010021751-A1 LOW SULFUR AND LOW METAL ADDITIVE FORMULATIONS FOR HIGH PERFORMANCE INDUSTRIAL OILS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2010-02-25 WO disclosed
EP-2118245-A2 MULTIPLE METAL CORROSION INHIBITOR Ciba Holding Inc. (CH) 2009-11-18 EP disclosed
EP-2087074-A1 STABILISED BIODIESEL FUEL COMPOSITIONS Ciba Holding Inc. (CH) 2009-08-12 EP disclosed
WO-2008095805-A2 MULTIPLE METAL CORROSION INHIBITOR CIBA HOLDING INC. (CH) 2008-08-14 WO disclosed
WO-2008065015-A1 STABILISED BIODIESEL FUEL COMPOSITIONS CIBA HOLDING INC. (CH) 2008-06-05 WO disclosed
EP-0160620-B1 METAL DEACTIVATORS CIBA-GEIGY AG (CH) 1989-09-13 EP disclosed