SCHEMBL19685813

SCHEMBL19685813

Cc1cn(C)c2ccc(N3c4ccccc4C(c4ccccc4)(c4ccccc4)c4ccccc43)cc2c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
KMT2A Q03164 4/20 0.33
LMNA P02545 1/20 0.33
EGLN1 Q9GZT9 1/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
MEN1 O00255 3/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TP53 P04637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ITGA4 P13612 1/20 0.31
ITGB7 P26010 1/20 0.31
MAOB P27338 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685732 0.91 EGLN1 (0.32) MGAMGAASIMGAM2LMNA
SCHEMBL19685812 0.89 MGAM (0.37) MGAMGAASIMGAM2KMT2A
SCHEMBL19685869 0.88 SCN2B (0.36) LMNAALDH1A1KDM4E
SCHEMBL19685819 0.86 MGAM (0.35) MGAMGAASIMGAM2KMT2A
SCHEMBL19685818 0.86 MGAM (0.35) MGAMGAASIMGAM2KMT2A
SCHEMBL19685824 0.84 KMT2A (0.40) KMT2ALMNANPC1RAB9AMEN1
SCHEMBL19685857 0.83 BRD4 (0.37) EGLN1POLB
SCHEMBL19685823 0.81 MAPK8 (0.33) LMNAALDH1A1KDM4E
SCHEMBL19685817 0.81 TP53 (0.35) MGAMGAASIMGAM2KMT2A
SCHEMBL19685736 0.80 MEN1 (0.35) MGAMGAASIMGAM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-14 US disclosed
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2017-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10714693-B2 Polycyclic compound and organic electroluminescence device including the same CYC1, CCNA1, CYCS MGAM 4557/4885GAA 4777/4885SI 4804/4885
US-20170352817-A1 POLYCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CYC1, CCNA1, CYCS MGAM 4557/4885GAA 4777/4885SI 4804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.