Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968000 | 0.95 | HSD11B1 (0.64) | HSD11B1IDH1 | |
| SCHEMBL1969928 | 0.92 | HSD11B1 (0.64) | HSD11B1IDH1 | |
| SCHEMBL1967883 | 0.89 | HSD11B1 (0.49) | HSD11B1IDH1 | |
| SCHEMBL1967306 | 0.88 | HSD11B1 (0.54) | HSD11B1IDH1 | |
| SCHEMBL1972606 | 0.88 | HSD11B1 (0.66) | HSD11B1IDH1 | |
| SCHEMBL1969150 | 0.87 | IDH1 (0.54) | HSD11B1IDH1 | |
| SCHEMBL1973459 | 0.86 | IDH1 (0.60) | HSD11B1IDH1 | |
| SCHEMBL1969227 | 0.86 | HSD11B1 (0.56) | HSD11B1IDH1 | |
| SCHEMBL1973870 | 0.84 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL1970196 | 0.84 | HSD11B1 (0.54) | HSD11B1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086939-B8 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2011-06-22 | — | — | EP | disclosed |
| EP-2086939-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | AstraZeneca AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008053194-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | disclosed |