Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 8/20 | 0.61 |
| ▸ | NR2E1 | Q9Y466 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12071826 | 0.85 | HTR1B (0.60) | NR2E1KDM4EKMT2AHTR1BALDH1A1 | |
| SCHEMBL541161 | 0.85 | HTR1B (0.60) | NR2E1KDM4EKMT2AHTR1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL28370503 | 0.84 | HTR1B (0.58) | NR2E1KDM4EKMT2AHTR1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL28883801 | 0.84 | HTR1B (0.58) | NR2E1KDM4EKMT2AHTR1BALDH1A1 | |
| SCHEMBL28331986 | 0.80 | CYP1A2 (0.64) | NR2E1CYP1A2KDM4EMEN1CYP2C19 | |
| SCHEMBL29029003 | 0.79 | NR2E1 (0.61) | NR2E1CYP1A2KDM4EMEN1CYP2C19 | |
| Oxalic Acid SCHEMBL9613804 | 0.79 | KMT2A (0.60) | NR2E1KDM4EMEN1KMT2AHTR1B | |
| SCHEMBL11413078 | 0.77 | CYP1A2 (0.69) | NR2E1CYP1A2KDM4EMEN1CYP2C19 | |
| SCHEMBL8761918 | 0.77 | NR2E1 (0.67) | NR2E1CYP1A2KDM4EMEN1CYP2C19 | |
| SCHEMBL12707712 | 0.76 | HTR1B (0.53) | NR2E1CYP1A2KDM4EMEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190270696-A1 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2019-09-05 | — | — | US | disclosed |
| WO-2017210371-A2 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2017-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270696-A1 | COMPOUNDS AS INHIBITORS OF SODIUM CHANNELS | SCN1B, CACNA1E, SCN2B | SCN4A 48/4885NR2E1 444/4885CYP1A2 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.