Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 14/20 | 0.36 |
| ▸ | IDH2 | P48735 | 3/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687218 | 0.94 | IDH1 (0.38) | IL1BIDH1IDH2 | |
| SCHEMBL19686686 | 0.80 | IDH1 (0.37) | IDH1IDH2NUDT1HRH4 | |
| SCHEMBL19687388 | 0.80 | KCNN2 (0.52) | IL1B | |
| SCHEMBL19686523 | 0.74 | IDH1 (0.44) | IDH1IDH2 | |
| SCHEMBL19687382 | 0.73 | KCNN2 (0.51) | IDH1 | |
| SCHEMBL19686272 | 0.73 | KCNN2 (0.51) | IDH1 | |
| SCHEMBL19687212 | 0.73 | KCNN2 (0.51) | IDH1 | |
| SCHEMBL19687174 | 0.71 | IDH1 (0.39) | IDH1IDH2 | |
| SCHEMBL19687150 | 0.71 | IDH1 (0.39) | IDH1IDH2 | |
| SCHEMBL19687151 | 0.70 | IDH1 (0.38) | IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |