Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 10/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | MIF | P14174 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.57 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.57 |
| ▸ | CBR1 | P16152 | 2/20 | 0.57 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15179344 | 1.00 | AKR1B10 (0.60) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL21555600 | 0.90 | AKR1B10 (0.61) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL18620897 | 0.86 | AKR1B10 (0.62) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL17644096 | 0.85 | AKR1B10 (0.61) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL15179178 | 0.84 | KMT2A (0.64) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL19686997 | 0.84 | KMT2A (0.64) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL18620902 | 0.82 | AKR1B10 (0.63) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL22800560 | 0.80 | AKR1B10 (0.70) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL19890381 | 0.79 | MEN1 (0.70) | AKR1B10AKR1B1NPC1RAB9AMIF | |
| SCHEMBL23960027 | 0.79 | AKR1B10 (0.68) | AKR1B10AKR1B1NPC1RAB9AMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349638-A1 | COMPANION DIAGNOSTIC TOOL FOR PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349638-A1 | COMPANION DIAGNOSTIC TOOL FOR PEPTIDOMIMETIC MACROCYCLES | TP53, TP53BP1, VHL | AKR1B10 3690/4885AKR1B1 3800/4885NPC1 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.