Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 12/20 | 0.36 |
| ▸ | IDH2 | P48735 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.30 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19686732 | 0.87 | KCNN3 (0.47) | KCNN2KCNN3IDH1IDH2 | |
| SCHEMBL19686291 | 0.78 | IDH1 (0.41) | KCNN2KCNN3IDH1IDH2PIM1 | |
| SCHEMBL19686284 | 0.76 | KCNN2 (0.49) | KCNN2KCNN3IDH1IDH2 | |
| SCHEMBL18748587 | 0.75 | IDH1 (0.49) | IDH1IDH2CCNT1 | |
| SCHEMBL19686887 | 0.75 | KCNN2 (0.48) | KCNN2KCNN3IDH1 | |
| SCHEMBL19687485 | 0.74 | IDH1 (0.42) | KCNN2KCNN3IDH1IDH2CCNT1 | |
| SCHEMBL19686941 | 0.72 | KCNN2 (0.46) | KCNN2KCNN3IDH1 | |
| SCHEMBL21165991 | 0.72 | KCNN2 (0.46) | KCNN2KCNN3IDH1 | |
| SCHEMBL19687319 | 0.72 | KCNN2 (0.46) | KCNN2KCNN3IDH1 | |
| SCHEMBL31127312 | 0.72 | KCNN2 (0.46) | KCNN2KCNN3IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |