Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 15/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31127312 | 0.86 | KCNN2 (0.46) | KCNN2KCNN3SLC34A1 | |
| SCHEMBL19686941 | 0.86 | KCNN2 (0.46) | KCNN2KCNN3SLC34A1 | |
| SCHEMBL31127324 | 0.80 | KCNN2 (0.42) | KCNN2KCNN3SLC34A1ADORA2A | |
| SCHEMBL21166179 | 0.80 | KCNN2 (0.42) | KCNN2KCNN3SLC34A1ADORA2A | |
| SCHEMBL21166129 | 0.75 | KCNN2 (0.39) | KCNN2KCNN3SLC34A1ADORA1ADORA2A | |
| SCHEMBL19686284 | 0.73 | KCNN2 (0.49) | KCNN2KCNN3 | |
| SCHEMBL19686887 | 0.73 | KCNN2 (0.48) | KCNN2KCNN3ADORA1ADORA2A | |
| SCHEMBL19686300 | 0.72 | KCNN2 (0.46) | KCNN2KCNN3SLC34A1 | |
| SCHEMBL19687319 | 0.72 | KCNN2 (0.46) | KCNN2KCNN3ADORA1ADORA2A | |
| SCHEMBL19686732 | 0.72 | KCNN3 (0.47) | KCNN2KCNN3SLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017139697-A9 | BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA | SYNLOGIC, INC. (US) | 2017-12-07 | — | — | WO | disclosed |