Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292172 | 0.85 | MEN1 (0.40) | MEN1KMT2AROCK2GRIN1GRIN2B | |
| SCHEMBL18292162 | 0.85 | MEN1 (0.42) | MEN1KMT2APARGROCK2PIK3R1 | |
| SCHEMBL18292174 | 0.80 | MEN1 (0.40) | MEN1KMT2AROCK2PIK3R1PIK3CA | |
| SCHEMBL20067410 | 0.80 | MEN1 (0.39) | MEN1KMT2APARGROCK2 | |
| SCHEMBL19687585 | 0.75 | MEN1 (0.45) | MEN1KMT2AROCK2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31092654 | 0.75 | KMT2A (0.40) | MEN1KMT2AROCK2GRIN1GRIN2B | |
| SCHEMBL19687584 | 0.74 | PARG (0.39) | MEN1KMT2APARGRAB9A | |
| SCHEMBL19687574 | 0.74 | PARG (0.40) | PARGGRIN1GRIN2B | |
| SCHEMBL22037356 | 0.73 | MEN1 (0.63) | MEN1KMT2A | |
| SCHEMBL19687588 | 0.73 | PARG (0.40) | PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |