Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18292174 | 0.77 | MEN1 (0.40) | MEN1KMT2AROCK2PGR | |
| SCHEMBL19687595 | 0.75 | MEN1 (0.45) | MEN1KMT2AROCK2KDM4EALDH1A1 | |
| SCHEMBL18292172 | 0.75 | MEN1 (0.40) | MEN1KMT2AROCK2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31092654 | 0.75 | KMT2A (0.40) | MEN1KMT2AROCK2KDM4EALDH1A1 | |
| SCHEMBL18292162 | 0.69 | MEN1 (0.42) | MEN1KMT2AROCK2KDM4EALDH1A1 | |
| SCHEMBL16030540 | 0.61 | NR1H2 (0.36) | — | |
| SCHEMBL5365892 | 0.59 | AR (0.65) | ROCK2 | |
| SCHEMBL30705681 | 0.58 | DCTPP1 (0.45) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19687623 | 0.57 | CCR9 (0.48) | — | |
| SCHEMBL16030262 | 0.56 | EHMT2 (0.43) | MEN1KMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |