Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 6/20 | 0.65 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809708 | 0.83 | SELE (0.76) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL19687718 | 0.80 | SELE (0.66) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL3799246 | 0.79 | SELE (1.00) | SELEVCAM1KDM4ETSHRCYP1A2 | |
| SCHEMBL4388091 | 0.76 | SELE (0.70) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL1604838 | 0.75 | SELE (0.69) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL19838140 | 0.73 | SELE (0.65) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL16031220 | 0.72 | SELE (0.64) | SELEVCAM1MEN1KMT2A | |
| SCHEMBL29737503 | 0.72 | SELE (0.64) | SELEVCAM1MEN1KMT2A | |
| SCHEMBL15111462 | 0.71 | SELE (0.50) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL22042459 | 0.71 | SELE (0.62) | SELEVCAM1HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017205972-A1 | SYSTEMS METHODS AND COMPOSITIONS FOR PREDICTING METASTASIS IN BLADDER CANCER | GENOMEDX BIOSCIENCES, INC. (CA) | 2017-12-07 | — | — | WO | disclosed |