SCHEMBL19688012

SCHEMBL19688012

CCC(Cc1ccccc1)c1ccccc1Br

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
SIGMAR1 Q99720 5/20 0.39
TAAR1 Q96RJ0 4/20 0.39
SLC6A2 P23975 2/20 0.39
MAOA P21397 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
CYP2A6 P11509 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
EPHX1 P07099 1/20 0.38
SLC18A2 Q05940 1/20 0.37
CYP2D6 P10635 1/20 0.37
TP53 P04637 1/20 0.37
ALPL P05186 1/20 0.36
POLB P06746 1/20 0.36
ALPG P10696 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254417 0.84 HTT (0.41) TAAR1MAOACYP2D6
SCHEMBL9856696 0.78 HTR2A (0.43) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL27946949 0.78 TSHR (0.55) TRPA1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL2572909 0.77 HTT (0.37) MAOAESR1ESR2
SCHEMBL10506241 0.77 IDO1 (0.38) TAAR1MAOA
SCHEMBL6678844 0.77 HTT (0.44) MAOACYP2D6
SCHEMBL10598919 0.76 TRPA1 (0.41) TRPA1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL11208144 0.76 PPARA (0.43) TRPA1SIGMAR1TAAR1SLC6A2MAOA
SCHEMBL3782807 0.76 CYP2C19 (0.35) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL7456485 0.75 EPHX1 (0.41) TRPA1SIGMAR1TAAR1SLC6A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017209488-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2017-12-07 WO disclosed