Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639749 | 0.91 | ELANE (0.47) | ELANEAVPR1B | |
| Benzene SCHEMBL19639826 | 0.91 | ELANE (0.46) | ELANEAVPR1B | |
| SCHEMBL21828992 | 0.90 | ELANE (0.47) | ELANECTSK | |
| SCHEMBL19639828 | 0.90 | ELANE (0.44) | ELANECTSK | |
| SCHEMBL19502974 | 0.83 | ELANE (0.52) | ELANECTSKAVPR1B | |
| SCHEMBL19639767 | 0.83 | ELANE (0.47) | ELANE | |
| SCHEMBL22562920 | 0.82 | ELANE (0.52) | ELANECTSKAVPR1B | |
| SCHEMBL21859895 | 0.82 | ELANE (0.52) | ELANECTSKAVPR1B | |
| Benzene SCHEMBL19639783 | 0.82 | ELANE (0.47) | ELANE | |
| SCHEMBL17819327 | 0.82 | ELANE (0.56) | ELANECTSKBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207433-A1 | HETETOCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF A DISEASE IN WHICH HNE IS IMPLICATED | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |