Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639806 | 0.80 | ELANE (0.43) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19639985 | 0.79 | ELANE (0.56) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19639792 | 0.78 | ELANE (0.46) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19684694 | 0.72 | ELANE (0.56) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19639773 | 0.71 | ELANE (0.53) | ELANECYP2C9CYP3A4 | |
| SCHEMBL21796123 | 0.71 | ELANE (0.54) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19639807 | 0.70 | ELANE (0.48) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19640024 | 0.70 | ELANE (0.54) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19639824 | 0.69 | ELANE (0.44) | ELANECYP2C9CYP3A4 | |
| SCHEMBL19640000 | 0.69 | ELANE (0.56) | ELANECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017207433-A9 | HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF A DISEASE IN WHICH HNE IS IMPLICATED | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-03-01 | — | — | WO | disclosed |
| WO-2017207433-A1 | HETETOCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF A DISEASE IN WHICH HNE IS IMPLICATED | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-12-07 | — | — | WO | disclosed |