Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133305 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1TRPA1KDM4ERAB9A | |
| SCHEMBL14451690 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1TRPA1KDM4ERAB9A | |
| SCHEMBL21100000 | 0.78 | ALDH1A1 (0.43) | TSHRALDH1A1TRPA1KDM4ERAB9A | |
| SCHEMBL25109162 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1TRPA1KDM4ERAB9A | |
| SCHEMBL22680156 | 0.72 | TSHR (0.38) | TSHRALDH1A1TRPA1KDM4ERAB9A | |
| SCHEMBL2439824 | 0.72 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL2439822 | 0.72 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL17122439 | 0.72 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL13287298 | 0.72 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4ERAB9ACYP1A2 | |
| SCHEMBL22478581 | 0.71 | ALDH1A1 (0.48) | TSHRALDH1A1KDM4ERAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210302-A1 | PET IMAGING WITH PD-L1 BINDING POLYPEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-12-07 | — | — | WO | disclosed |