Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589447 | 0.95 | MEN1 (0.65) | MEN1KMT2AHTR2CTACR1CHRNB4 | |
| SCHEMBL23323077 | 0.95 | MEN1 (0.65) | MEN1KMT2AHTR2CTACR1CHRNB4 | |
| SCHEMBL469013 | 0.95 | MEN1 (0.65) | MEN1KMT2AHTR2CTACR1CHRNB4 | |
| SCHEMBL25247513 | 0.83 | ATM (0.45) | MEN1KMT2AHTR2CTACR1POLB | |
| SCHEMBL25238785 | 0.83 | ATM (0.45) | MEN1KMT2AHTR2CTACR1POLB | |
| SCHEMBL25289106 | 0.83 | ATM (0.45) | MEN1KMT2AHTR2CTACR1POLB | |
| Hydrochloric Acid SCHEMBL31648321 | 0.81 | KMT2A (0.57) | MEN1KMT2AHTR2CTACR1CHRNB4 | |
| SCHEMBL24168763 | 0.81 | MEN1 (0.54) | MEN1KMT2AHTR2CTACR1 | |
| SCHEMBL22720995 | 0.81 | MEN1 (0.60) | MEN1KMT2AHTR2CTACR1CHRNB4 | |
| SCHEMBL31648821 | 0.81 | MEN1 (0.60) | MEN1KMT2AHTR2CTACR1CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752640-B2 | Compounds active towards bromodomains | NUEVOLUTION A/S (DK) | 2020-08-25 | — | — | US | disclosed |
| US-20170349607-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION A/S (DK) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349607-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | BRD4, BRD3, BRDT | MEN1 3579/4885KMT2A 253/4885HTR2C 3194/4885 |
| US-10752640-B2 | Compounds active towards bromodomains | BRD4, BRD3, BRDT | MEN1 3579/4885KMT2A 253/4885HTR2C 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.