Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469013 | 0.85 | MEN1 (0.65) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL23323077 | 0.85 | MEN1 (0.65) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL29589447 | 0.85 | MEN1 (0.65) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL31648586 | 0.84 | MEN1 (0.60) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL31648821 | 0.84 | MEN1 (0.60) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL27439720 | 0.84 | MEN1 (0.56) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| Hydrochloric Acid SCHEMBL31648191 | 0.83 | MEN1 (0.58) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL31444210 | 0.83 | MEN1 (0.51) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| Hydrochloric Acid SCHEMBL31648321 | 0.82 | KMT2A (0.57) | MEN1KMT2AHSD11B1PDCD1LG2CD274 | |
| SCHEMBL19689047 | 0.81 | MEN1 (0.59) | MEN1KMT2AHSD11B1PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020239073-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2020-12-03 | — | — | WO | disclosed |