⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486284 | 1.00 | — | — | |
| SCHEMBL18486251 | 0.85 | PDE4A (0.34) | — | |
| SCHEMBL18486404 | 0.85 | PDE4A (0.34) | — | |
| SCHEMBL18486371 | 0.81 | SLC28A2 (0.37) | — | |
| SCHEMBL19689083 | 0.81 | SLC28A2 (0.37) | — | |
| SCHEMBL18486383 | 0.80 | STING1 (0.35) | — | |
| SCHEMBL18486384 | 0.80 | STING1 (0.35) | — | |
| SCHEMBL19689099 | 0.78 | SLC28A2 (0.32) | — | |
| SCHEMBL18486311 | 0.77 | — | — | |
| SCHEMBL18486314 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342819-B2 | Oligonucleotide having non-natural nucleotide at 5′-terminal thereof | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170354673-A1 | OLIGONUCLEOTIDE HAVING NON-NATURAL NUCLEOTIDE AT 5'-TERMINAL THEREOF | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-12-14 | — | — | US | disclosed |