SCHEMBL19689518

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19689540	0.88	NR1H4 (0.46)	NR1H4GABRB3GABRA2GABRB2OPRL1
	SCHEMBL19698948	0.86	NR1H4 (0.45)	NR1H4GABRB3GABRA2GABRB2OPRL1
	SCHEMBL1095874	0.83	NR1H4 (0.42)	NR1H4GABRB2KCNJ5KCNJ3
	SCHEMBL20833795	0.81	NR1H4 (0.40)	NR1H4GABRB2
	SCHEMBL20833740	0.81	NR1H4 (0.43)	NR1H4KCNJ5KCNJ3
	SCHEMBL2772447	0.78	NR1H4 (0.39)	NR1H4GABRB2KCNJ5KCNJ3
	SCHEMBL20833875	0.75	NR1H4 (0.38)	NR1H4KCNJ5KCNJ3OPRL1
	SCHEMBL2773464	0.75	NR1H4 (0.38)	NR1H4KCNJ5KCNJ3
	SCHEMBL2775151	0.74	NR1H4 (0.37)	NR1H4GABRB3GABRA2GABRB2KCNJ5
	SCHEMBL19689539	0.73	NR1H4 (0.39)	NR1H4GABRB3GABRA2GABRB2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.