SCHEMBL19689539

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1097050	0.86	PDE4D (0.43)	NR1H4KDM4EHSD17B10HTTPOLB
	SCHEMBL30035480	0.84	NOD2 (0.41)	KDM4EHTTPOLBMEN1ALDH1A1
	SCHEMBL24087503	0.84	SMN1; SMN2 (0.45)	NR1H4KDM4EHTTPOLBTP53
	SCHEMBL2773569	0.82	PDE4D (0.41)	NR1H4KDM4EHSD17B10HTTPOLB
	SCHEMBL20833878	0.81	HTT (0.40)	NR1H4KDM4EHSD17B10HTTPOLB
	SCHEMBL2773589	0.79	TP53 (0.40)	KDM4EHSD17B10HTTPOLBTP53
	SCHEMBL24087507	0.79	TP53 (0.43)	PKMKDM4EHTTPOLBTP53
	SCHEMBL24087545	0.78	NOD2 (0.38)	KDM4EHTTPOLBTP53MEN1
	SCHEMBL19698948	0.76	NR1H4 (0.45)	NR1H4GABRB3GABRA2GABRB2MAPK1
	SCHEMBL19689540	0.72	NR1H4 (0.46)	NR1H4GABRB3GABRA2GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.