Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12044749 | 0.87 | HTR3A (0.53) | HTR3ACHRNA7HTR3EHTR3BHTR3D | |
| SCHEMBL1966800 | 0.87 | HTR3A (0.53) | HTR3ACHRNA7HTR3EHTR3BHTR3D | |
| SCHEMBL1963584 | 0.87 | HTR3A (0.54) | HTR3ACHRNA7HTR3EHTR3BHTR3D | |
| SCHEMBL1964599 | 0.85 | HTR3A (0.56) | HTR3ACHRNA7 | |
| SCHEMBL1964306 | 0.84 | HTR3A (0.59) | HTR3ACHRNA7 | |
| SCHEMBL1963582 | 0.83 | HTR3A (0.59) | HTR3ACHRNA7 | |
| SCHEMBL12044741 | 0.81 | MAPT (0.54) | HTR3ACHRNA7 | |
| SCHEMBL12339954 | 0.80 | CHRNA7 (0.51) | HTR3ACHRNA7HTR3EHTR3BHTR3D | |
| SCHEMBL1963490 | 0.80 | HTR3A (0.49) | HTR3ACHRNA7 | |
| SCHEMBL12044747 | 0.80 | HTR3A (0.49) | HTR3ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |