Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.72 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.72 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.72 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969049 | 0.95 | S1PR1 (0.80) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL3629337 | 0.91 | S1PR1 (0.79) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1964408 | 0.89 | S1PR1 (0.77) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1963847 | 0.88 | S1PR1 (0.84) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1966681 | 0.87 | S1PR1 (0.69) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1966562 | 0.87 | S1PR1 (0.74) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1964968 | 0.86 | S1PR1 (0.82) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1966992 | 0.85 | S1PR1 (0.70) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1966424 | 0.85 | S1PR1 (0.80) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1965526 | 0.85 | S1PR1 (0.62) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334670-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | Almirall S.A. (ES) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010043377-A1 | NEW 2-AMIDOTHIADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2010-04-22 | — | — | WO | disclosed |