Homidium

Homidium

SCHEMBL19690770

CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21.[O-2]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.97
▸ KMT2A Q03164 5/20 0.97
▸ MAPT P10636 5/20 0.97
▸ BLM P54132 4/20 0.97
▸ KDM4E B2RXH2 4/20 0.97
▸ HPGD P15428 4/20 0.97
▸ HTT P42858 4/20 0.97
▸ CYP3A4 P08684 3/20 0.97
▸ THRB P10828 3/20 0.97
▸ CASP1 P29466 3/20 0.97
▸ RECQL P46063 3/20 0.97
▸ CASP7 P55210 3/20 0.97
▸ TERT O14746 3/20 0.97
▸ ALDH1A1 P00352 3/20 0.97
▸ MAPK1 P28482 3/20 0.97
▸ HSD17B10 Q99714 3/20 0.97
▸ MITF O75030 2/20 0.97
▸ NSD2 O96028 2/20 0.97
▸ LMNA P02545 2/20 0.97
▸ TP53 P04637 2/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homidium SCHEMBL27609 0.99 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL31511751 0.99 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL21647365 0.99 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL29391335 0.99 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL612343 0.97 MEN1 (0.97) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL1879927 0.97 MEN1 (0.97) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL11023665 0.97 MEN1 (0.97) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL3025214 0.97 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL20520 0.97 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E
Homidium SCHEMBL7751164 0.97 MEN1 (1.00) MEN1KMT2AMAPTBLMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118217380-A Application of JWA polypeptide in preparing anti-hepatitis or anti-hepatic fibrosis medicine 周建伟 2024-06-21 — — CN disclosed
WO-2024026841-A1 DRUG-LOADED ERYTHROCYTE MEMBRANE NANOPARTICLE, METHOD FOR PREPARING SAME, AND USE THEREOF 苏州大学 2024-02-08 — — WO disclosed
CN-116509902-B Probiotic agent for improving mental diseases caused by environmental pollution by adjusting intestinal-brain axis and application thereof 微康益生菌(苏州)股份有限公司 2023-11-21 — — CN disclosed
CN-117045665-A New application of acteoside 新疆医科大学第一附属医院 2023-11-14 — — CN disclosed
JP-2023121866-A AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS マム ホールディングス オブ ウエスト フロリダ, リミテッド ライアビリティ カンパニー 2023-08-31 — — JP disclosed
CN-116509902-A Probiotic agent for improving mental diseases caused by environmental pollution by adjusting intestinal-brain axis and application thereof 微康益生菌(苏州)股份有限公司 2023-08-01 — — CN disclosed
CN-113509471-B Application of AKT2 inhibitor in preparation of medicine for treating doxorubicin-induced myocardial injury 中国药科大学 2023-06-13 — — CN disclosed
CN-112999153-B Nano micelle carrying chemotherapeutic drug/photosensitizer and preparation method and application thereof 苏州大学 2023-04-07 — — CN disclosed
US-20230021477-A1 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS MAM Holdings of West Florida, L.L.C. 2023-01-26 — — US disclosed
WO-2022188046-A1 CHEMOTHERAPEUTIC DRUG-/PHOTOSENSITIZER-LOADED NANOMICELLE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 苏州大学 2022-09-15 — — WO disclosed
CN-114014875-B Degradable near-infrared photosensitizer, preparation method and application thereof 北京协同创新研究院 2022-08-19 — — CN disclosed
CN-113735886-B PDT compounds, methods of preparation and uses thereof 北京大学 2022-06-03 — — CN disclosed
CN-114014875-A Degradable near-infrared photosensitizer, preparation method and application thereof 北京协同创新研究院 2022-02-08 — — CN disclosed
EP-3468571-B1 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS MAM HOLDINGS OF WEST FLORIDA L L C (US) 2022-01-26 — — EP disclosed
CN-113735886-A PDT compounds, methods of preparation and uses thereof 北京大学 2021-12-03 — — CN disclosed
EP-3468571-A1 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS Mam Holdings Of West Florida, L.L.C. (US) 2019-04-17 — — EP disclosed
US-20180140641-A1 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS MAM Holdings of West Florida, L.L.C. 2018-05-24 — — US disclosed
WO-2017218535-A1 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS MAM Holdings of West Florida, L.L.C. (US) 2017-12-21 — — WO disclosed
US-20170354692-A1 AMNIOTIC FLUID FORMULATION FOR TREATMENT OF LUNG DISORDERS MAM Holdings of West Florida, L.L.C. 2017-12-14 — — US disclosed
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