Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Homidium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 3/20 | 1.00 |
| ▸ | CASP1 | P29466 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | CASP7 | P55210 | 3/20 | 1.00 |
| ▸ | TERT | O14746 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | MITF | O75030 | 2/20 | 1.00 |
| ▸ | NSD2 | O96028 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homidium SCHEMBL29376492 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL7751164 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL29498260 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL3025214 | 1.00 | MEN1 (1.00) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL8777149 | 0.99 | MEN1 (0.97) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL8173023 | 0.99 | MEN1 (0.97) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL7934374 | 0.99 | MEN1 (0.97) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL2715995 | 0.99 | MEN1 (0.97) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL7865388 | 0.99 | MEN1 (0.97) | MEN1KMT2AMAPTBLMKDM4E | |
| Homidium SCHEMBL2715993 | 0.99 | MEN1 (0.97) | MEN1KMT2AMAPTBLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 151459 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139329-A1 | METHOD TO CHARACTERIZE NUCLEIC ACID | ICHORtec GmbH (DE) | 2026-05-21 | — | — | US | claimed |
| US-20260137650-A1 | MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) | 11949098 CANADA INC (CA) | 2026-05-21 | — | — | US | claimed |
| WO-2026102332-A1 | NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF | Blaze Bioscience, Inc. (US) | 2026-05-15 | — | — | WO | claimed |
| CN-122012795-A | Method for identifying melon low-temperature weak light phenotype and special primer thereof | 宁波市农业科学研究院 | 2026-05-12 | — | — | CN | claimed |
| EP-4737898-A2 | SEPARATION AND ISOLATION OF NUCLEIC ACIDS USING AFFINITY LIGANDS BOUND TO A SOLID SURFACE | EMP Biotech GmbH (DE) | 2026-05-06 | — | — | EP | claimed |
| US-12618835-B2 | Multiplex microelectrode array for detection of proteases as biomarkers | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2026-05-05 | — | — | US | claimed |
| US-20260117275-A1 | METHODS FOR QUANTITATING VIRAL CAPSIDS | SARTORIUS BIOANALYTICAL INSTRUMENTS, INC. (US) | 2026-04-30 | — | — | US | claimed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | claimed |
| EP-4720336-A1 | CONDENSED LOOP-MEDIATED ISOTHERMAL AMPLIFICATION | Sherlock Biosciences, Inc. (US) | 2026-04-08 | — | — | EP | claimed |
| US-20260092924-A1 | NON-ENZYMATIC GLOW ASSAYS | UNIVERSITY OF HOUSTON SYSTEM (US) | 2026-04-02 | — | — | US | claimed |
| US-4391688-A | Electrophoresis system for multiple agarose slab gels | INSTITUT ARMAND-FRAPPIER (CA) | 1983-07-05 | — | — | US | claimed |
| EP-0057553-A1 | Method for the fluorescent detection of damaged DNA and kit for use therein | ATOMIC ENERGY OF CANADA LIMITED (CA) | 1982-08-11 | — | — | EP | claimed |
| US-4335226-A | Adsorbent for the affinity-specific separation of macromolecular materials | BOEHRINGER MANNHEIM GMBH (DE) | 1982-06-15 | — | — | US | claimed |
| US-4270924-A | Diagnostic method for detecting cancer | BAYLOR COLLEGE OF MEDICINE, | 1981-06-02 | — | — | US | claimed |
| US-4257774-A | Intercalation inhibition assay for compounds that interact with DNA or RNA | MELOY LABORATORIES, INC. (US) | 1981-03-24 | — | — | US | claimed |
| US-4207200-A | Soluble complex former for the affinity specific separation of macromolecular substances, its preparation and its use | BUNEMANN HANS (DE) | 1980-06-10 | — | — | US | claimed |
| EP-0008826-A2 | Method and apparatus for counting bacteria in a bacteria-containing suspension, method for fluorescence staining of bacteria, and method for separating bacteria from a sample | Metrofoss K/S (DK) | 1980-03-19 | — | — | EP | claimed |
| US-4146604-A | STAINING WITH MIXTURE OF FLUORESCENT DYES AND SENSITIZERS | BLOCK ENGINEERING, INC. (US) | 1979-03-27 | — | — | US | claimed |
| US-4119521-A | Fluorescent derivatives of activated polysaccharides | Turner, Stephen (US) | 1978-10-10 | — | — | US | claimed |
| US-4024242-A | TRYPANOSOMES, PHENANTHRINE DERIVATIVES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | claimed |