Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066 | 0.94 | APP (1.00) | APPCYP1A2ESR1ESR2SNCA | |
| Phosphonic Acid SCHEMBL2345109 | 0.94 | APP (0.78) | APPCYP1A2ESR1ESR2SNCA | |
| SCHEMBL29456578 | 0.93 | APP (0.97) | APPCYP1A2ESR1ESR2SNCA | |
| Ammonia Solution, Strong SCHEMBL29419058 | 0.93 | APP (0.97) | APPCYP1A2ESR1ESR2SNCA | |
| SCHEMBL7113427 | 0.93 | APP (0.97) | APPCYP1A2ESR1ESR2SNCA | |
| SCHEMBL1095367 | 0.93 | APP (0.97) | APPCYP1A2ESR1ESR2SNCA | |
| Phosphoric Acid SCHEMBL307361 | 0.89 | APP (0.89) | APPCYP1A2ESR1ESR2SNCA | |
| Methoxymethane SCHEMBL2784008 | 0.89 | APP (0.89) | APPCYP1A2ESR1ESR2SNCA | |
| SCHEMBL532223 | 0.88 | APP (0.86) | APPCYP1A2ESR1ESR2SNCA | |
| Alcohol SCHEMBL6810203 | 0.88 | APP (0.86) | APPCYP1A2ESR1ESR2SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530404-B2 | Enzyme immobilization in hierarchical metal-organic frameworks | NORTHWESTERN UNIVERSITY (US) | 2022-12-20 | — | — | US | disclosed |
| US-20190112591-A1 | ENZYME IMMOBILIZATION IN HIERARCHICAL METAL-ORGANIC FRAMEWORKS | NORTHWESTERN UNIVERSITY | 2019-04-18 | — | — | US | disclosed |
| WO-2017213871-A2 | ENZYME IMMOBILIZATION IN HIERARCHICAL METAL-ORGANIC FRAMEWORKS | NORTHWESTERN UNIVERSITY (US) | 2017-12-14 | — | — | WO | disclosed |