SCHEMBL1095367

SCHEMBL1095367

O=c1ccc2nc3ccc(O)cc3oc-2c1.[NaH]

nearest known ligand 0.97

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 0.97
CYP1A2 P05177 1/20 0.58
ESR1 P03372 4/20 0.46
ESR2 Q92731 4/20 0.46
SNCA P37840 1/20 0.45
PDE4D Q08499 1/20 0.45
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
PLEC Q15149 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8066 0.98 APP (1.00) APPCYP1A2ESR1ESR2SNCA
SCHEMBL29456578 0.97 APP (0.97) APPCYP1A2ESR1ESR2SNCA
Ammonia Solution, Strong SCHEMBL29419058 0.97 APP (0.97) APPCYP1A2ESR1ESR2SNCA
SCHEMBL7113427 0.97 APP (0.97) APPCYP1A2ESR1ESR2SNCA
Phosphonic Acid SCHEMBL19693027 0.93 APP (0.89) APPCYP1A2ESR1ESR2SNCA
Phosphoric Acid SCHEMBL307361 0.93 APP (0.89) APPCYP1A2ESR1ESR2SNCA
Methoxymethane SCHEMBL2784008 0.93 APP (0.89) APPCYP1A2ESR1ESR2SNCA
Acetic Acid SCHEMBL233000 0.92 APP (0.86) APPCYP1A2ESR1ESR2SNCA
SCHEMBL532223 0.92 APP (0.86) APPCYP1A2ESR1ESR2SNCA
Alcohol SCHEMBL6810203 0.92 APP (0.86) APPCYP1A2ESR1ESR2SNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669043-A Fluorescent probe for identifying cysteine, homocysteine, glutathione and hydrogen sulfide and preparation method thereof 南宁师范大学 2020-01-10 CN claimed
CN-105693651-A Organic small-molecule probe for detecting zero-valent palladium and preparation method thereof 华南理工大学 2016-06-22 CN claimed
CN-103805170-A Specific fluorescent probe for identifying hydrogen sulfide and application of probe CHANGSHU RES INST CO LTD DALIAN UNIVERSITY OF TECHNOLOGY 2014-05-21 CN claimed
EP-2568288-A1 Means and methods for staining acid-fast cells Koninklijke Philips Electronics N.V. (NL) 2013-03-13 EP claimed
EP-4225931-A1 OXYGEN-INSENSITIVE ELECTROCHEMICAL BIOSENSOR AND METHODS OF USE THEREOF Trividia Health, Inc. (US) 2023-08-16 EP disclosed
CN-116569031-A Oxygen insensitive electrochemical biosensor and method of use thereof 三伟达保健公司 2023-08-08 CN disclosed
US-11530404-B2 Enzyme immobilization in hierarchical metal-organic frameworks NORTHWESTERN UNIVERSITY (US) 2022-12-20 US disclosed
US-11519014-B2 Specific substrate of an ALDH isoenzyme ADVANCED BIODESIGN (FR) 2022-12-06 US disclosed
US-20220112536-A1 OXYGEN-INSENSITIVE ELECTROCHEMICAL BIOSENSOR AND METHODS OF USE THEREOF TRIVIDIA HEALTH, INC. 2022-04-14 US disclosed
US-11220703-B2 Fluorometric and colorimetric quantification techniques with autonomously and reversibly stalling catalytic signal amplification University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-01-11 US disclosed
WO-2021261925-A1 COMPOUND, COMPOSITION COMPRISING SAME, AND FLUORESCENCE SENSOR FOR DETECTING ACETYLCHOLINESTERASE ACTIVITY 이화여자대학교 산학협력단 2021-12-30 WO disclosed
CN-107556303-B Compound, synthesis method thereof, kit prepared from compound and application of kit in glutathione detection 潍坊医学院 2021-08-20 CN disclosed
EP-0423891-B1 Method for recording and detecting a pattern of ionizing radiation AGFA GEVAERT NV (BE) 1995-09-13 EP disclosed
EP-0694164-A4 METHOD FOR OPTICALLY MEASURING CHEMICAL ANALYTES UNIV MARYLAND (US) 1994-06-22 EP disclosed
EP-0396642-B1 ENZYME CONTROLLED RELEASE SYSTEM POLAROID CORP (US) 1994-05-11 EP disclosed
US-5208332-A Optical probe for the cytochrome P-450 cholesterol side chain cleavage enzyme THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1993-05-04 US disclosed
WO-1992019957-A2 METHOD FOR OPTICALLY MEASURING CHEMICAL ANALYTES UNIVERSITY OF MARYLAND AT BALTIMORE (US) 1992-11-12 WO disclosed
US-5112739-A Quinone-methide elimination POLAROID CORPORATION (US) 1992-05-12 US disclosed
US-5110725-A Optical probe for the cytochrome P-450 cholesterol side chain cleavage enzyme THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1992-05-05 US disclosed
EP-0423891-A1 Method for recording and detecting a pattern of ionizing radiation AGFA-GEVAERT N.V. (BE) 1991-04-24 EP disclosed