Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | UTRN | P46939 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL307361 | 0.83 | APP (0.89) | APPCYP1A2MEN1POLBKMT2A | |
| Phosphoric Acid SCHEMBL307362 | 0.80 | APP (0.61) | APPCYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL8066 | 0.80 | APP (1.00) | APPCYP1A2MEN1POLBKMT2A | |
| Pyrophosphoric Acid SCHEMBL12479167 | 0.79 | APP (0.80) | APPCYP1A2MEN1POLBKMT2A | |
| Pyridine SCHEMBL591180 | 0.79 | APP (0.74) | APPCYP1A2MEN1POLBKMT2A | |
| SCHEMBL7113427 | 0.78 | APP (0.97) | APPCYP1A2MEN1POLBKMT2A | |
| Pyridine SCHEMBL8601041 | 0.77 | APP (0.54) | APPCYP1A2ALDH1A1MEN1POLB | |
| SCHEMBL1635563 | 0.77 | APP (0.68) | APPCYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL14243596 | 0.77 | APP (0.68) | APPCYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL10167845 | 0.76 | APP (0.68) | APPCYP1A2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530404-B2 | Enzyme immobilization in hierarchical metal-organic frameworks | NORTHWESTERN UNIVERSITY (US) | 2022-12-20 | — | — | US | disclosed |
| US-20190112591-A1 | ENZYME IMMOBILIZATION IN HIERARCHICAL METAL-ORGANIC FRAMEWORKS | NORTHWESTERN UNIVERSITY | 2019-04-18 | — | — | US | disclosed |
| WO-2017213871-A2 | ENZYME IMMOBILIZATION IN HIERARCHICAL METAL-ORGANIC FRAMEWORKS | NORTHWESTERN UNIVERSITY (US) | 2017-12-14 | — | — | WO | disclosed |