Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13648662 | 0.83 | APP (0.55) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL14243596 | 0.81 | APP (0.68) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL1093966 | 0.81 | APP (0.68) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL3363350 | 0.81 | RAB9A (0.47) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL8066 | 0.81 | APP (1.00) | APPCYP1A2MEN1KMT2APOLB | |
| SCHEMBL29456578 | 0.80 | APP (0.97) | APPCYP1A2MEN1KMT2APOLB | |
| SCHEMBL29456527 | 0.80 | APP (0.67) | APPCYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7113427 | 0.80 | APP (0.97) | APPCYP1A2MEN1KMT2APOLB | |
| Ammonia Solution, Strong SCHEMBL29419058 | 0.80 | APP (0.97) | APPCYP1A2MEN1KMT2APOLB | |
| SCHEMBL1095367 | 0.80 | APP (0.97) | APPCYP1A2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240131047-A1 | SMALL MOLECULE INHIBITORS OF CD38 AS IMMUNOSUPPRESSANTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-04-25 | — | — | US | disclosed |
| EP-4288053-A1 | SMALL MOLECULE INHIBITORS OF CD38 AS IMMUNOSUPPRESSANTS | Ohio State Innovation Foundation (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022170265-A1 | SMALL MOLECULE INHIBITORS OF CD38 AS IMMUNOSUPPRESSANTS | OHIO STATE INNOVATION FOUNDATION (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-108440482-A | A kind of preparation method and application of the near-infrared ratio fluorescent probe of real-time detection mercury ion | 军事科学院军事医学研究院环境医学与作业医学研究所 | 2018-08-24 | — | — | CN | disclosed |
| US-20170334865-A1 | DDR2 INHIBITORS AND METHODS OF USING | WASHINGTON UNIVERSITY (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334865-A1 | DDR2 INHIBITORS AND METHODS OF USING | WASHINGTON UNIVERSITY (US) | 2017-11-23 | — | — | US | disclosed |
| EP-1786828-B1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-7932050-B2 | Enzymatic substrates derived from phenoxazinone and their use as developers in detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2011-04-26 | — | — | US | disclosed |
| US-20100028926-A1 | Novel enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2010-02-04 | — | — | US | disclosed |
| US-7626018-B2 | Enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity | bioMérieux (FR) | 2009-12-01 | — | — | US | disclosed |
| US-20080293094-A1 | Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity | BIOMERIEUX (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1786828-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | BIOMERIEUX (FR) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006030119-A1 | NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY | bioMérieux (FR) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334865-A1 | DDR2 INHIBITORS AND METHODS OF USING | DDR2, DDR1, DDRGK1 | APP 3057/4885CYP1A2 4799/4885KDM4E 3873/4885 |
| US-20240131047-A1 | SMALL MOLECULE INHIBITORS OF CD38 AS IMMUNOSUPPRESSANTS | CD38, CD2, CD58 | APP 4091/4885CYP1A2 4276/4885KDM4E 2787/4885 |
| US-20080293094-A1 | Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity | PEPD, CTRL, PREP | APP 210/4885CYP1A2 174/4885KDM4E 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.