Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13386565 | 0.90 | ELANE (0.61) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL13386569 | 0.90 | ELANE (0.61) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL134146 | 0.86 | NPC1 (0.67) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16838646 | 0.81 | ELANE (0.50) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL13556324 | 0.80 | ELANE (0.65) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1589852 | 0.80 | NPC1 (0.72) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1589854 | 0.80 | NPC1 (0.72) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12723710 | 0.77 | NPC1 (0.72) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL16838637 | 0.77 | KMT2A (0.44) | ELANENPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1590366 | 0.77 | NPC1 (0.71) | ELANENPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839640-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2017-12-12 | — | — | US | disclosed |