Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046875 | 0.73 | KMT2A (0.33) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3130070 | 0.71 | P2RX7 (0.56) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9926539 | 0.70 | SETDB1 (0.57) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11763132 | 0.69 | GAA (0.51) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL23565221 | 0.68 | P2RX7 (0.59) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL8279448 | 0.67 | SLC6A4 (0.57) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL30435034 | 0.67 | SLC6A4 (0.57) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL15682778 | 0.67 | HDAC1 (0.54) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL23997640 | 0.67 | IDO1 (0.52) | P2RX7HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL15682815 | 0.66 | P2RX7 (0.50) | P2RX7HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214413-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS HISTONE DEMETHYLASE INHIBITORS | Chrysalis, Inc. (US) | 2017-12-14 | — | — | WO | disclosed |