Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.45 |
| ▸ | NOS3 | P29474 | 5/20 | 0.45 |
| ▸ | NOS1 | P29475 | 4/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19448469 | 0.81 | CTSA (0.46) | NOS2NOS3NOS1BAZ2BCNR1 | |
| SCHEMBL25222774 | 0.79 | NOS2 (0.50) | NOS2NOS3NOS1 | |
| SCHEMBL6027026 | 0.79 | NOS2 (0.50) | NOS2NOS3NOS1 | |
| SCHEMBL19380938 | 0.78 | NQO2 (0.47) | NOS2NOS3NOS1 | |
| SCHEMBL2089670 | 0.77 | PLK1 (0.43) | BAZ2BNPC1RAB9AMAPK8MAPK9 | |
| SCHEMBL22593023 | 0.76 | SMN1; SMN2 (0.45) | BAZ2BCNR1NPC1POLBRAB9A | |
| SCHEMBL19662208 | 0.75 | BRD4 (0.47) | BAZ2BCNR1NPC1POLBRAB9A | |
| SCHEMBL17512543 | 0.74 | BAZ2B (0.43) | BAZ2BCNR1NPC1POLBRAB9A | |
| SCHEMBL16572978 | 0.74 | HSP90AB1 (0.50) | BAZ2BCNR1NPC1POLBRAB9A | |
| SCHEMBL22593139 | 0.74 | BRD4 (0.46) | BAZ2BCNR1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214413-A1 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS HISTONE DEMETHYLASE INHIBITORS | Chrysalis, Inc. (US) | 2017-12-14 | — | — | WO | disclosed |