Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | JAK2 | O60674 | 2/20 | 0.58 |
| ▸ | JAK3 | P52333 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531252 | 0.89 | CDC7 (0.53) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL6149056 | 0.86 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL13531230 | 0.84 | MAPT (0.50) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL27681418 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL27541726 | 0.82 | MAPT (0.52) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL1965857 | 0.80 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL31091353 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL2564440 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL24484277 | 0.79 | MAPK1 (0.44) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA | |
| SCHEMBL4593201 | 0.79 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| EP-2334643-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | Actelion Pharmaceuticals Ltd. (CH) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010044054-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-04-22 | — | — | WO | disclosed |
| US-20100015382-A1 | AZO METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-0112617-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4581220-A | CURED RESIDUE OF ZIRCONIUM SOLUTION | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1986-04-08 | — | — | US | disclosed |
| US-4576815-A | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1986-03-18 | — | — | US | disclosed |
| EP-0112617-A1 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | ALDH1A1 2292/4885SMN1; SMN2 3751/4885MAPT 1419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.