Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968836 | 0.79 | MAOA (0.53) | PHGDHNOTUMACACB | |
| SCHEMBL15025140 | 0.79 | NOTUM (0.44) | PHGDHNOTUMHDAC6ACACBESR1 | |
| SCHEMBL2930510 | 0.78 | ESR2 (0.54) | PHGDHNOTUMHDAC6ACACBESR1 | |
| SCHEMBL13405606 | 0.77 | NOTUM (0.46) | PHGDHNOTUMHDAC6ACACBESR1 | |
| SCHEMBL16759871 | 0.76 | ESR2 (0.53) | PHGDHNOTUMHDAC6ACACBESR1 | |
| SCHEMBL3874010 | 0.76 | ESR2 (0.72) | PHGDHNOTUMHDAC6ACACBESR1 | |
| SCHEMBL29963966 | 0.76 | ESR2 (0.72) | PHGDHNOTUMHDAC6ACACBESR1 | |
| SCHEMBL17993834 | 0.76 | TMEM97 (0.47) | PHGDHNOTUMHDAC6ACACBDPP7 | |
| SCHEMBL29964619 | 0.76 | ACACB (0.49) | PHGDHNOTUMHDAC6ACACBDPP7 | |
| SCHEMBL16624019 | 0.76 | ACACB (0.52) | PHGDHNOTUMACACBDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214539-A1 | FLUORINATED 2-AMINO-4-(SUBSTITUTED AMINO)PHENYL CARBAMATE DERIVATIVES | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-12-14 | — | — | WO | disclosed |