SCHEMBL1969866

SCHEMBL1969866

C=CCOC(=O)CCS.CC(O)=S

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
PKM P14618 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 4/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.34
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
EPHX2 P34913 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
TRPV1 Q8NER1 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1460906 0.89
SCHEMBL11320666 0.87 TSHR (0.53) TSHRPKMSMN1; SMN2TDP1ALDH1A1
SCHEMBL10598502 0.87 TSHR (0.53) TSHRPKMSMN1; SMN2TDP1ALDH1A1
SCHEMBL10581669 0.87 TSHR (0.53) TSHRPKMSMN1; SMN2TDP1ALDH1A1
SCHEMBL11275951 0.77 TSHR (0.61) TSHRPKMSMN1; SMN2TDP1ALDH1A1
SCHEMBL56403 0.76 TSHR (0.63) TSHRPKMSMN1; SMN2TDP1ALDH1A1
SCHEMBL9064888 0.76 TSHR (0.59) TSHRPKMSMN1; SMN2TDP1ALDH1A1
Methacrylic Acid SCHEMBL22345178 0.76 TSHR (0.55) TSHRPKMSMN1; SMN2TDP1ALDH1A1
Acetic Acid SCHEMBL27779067 0.75 TSHR (0.48) TSHRPKMSMN1; SMN2TDP1ALDH1A1
SCHEMBL720931 0.75 TSHR (0.58) TSHRPKMSMN1; SMN2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382640-A Polymers with pendant thio-acyl groups used as graft polymerization sites when deprotected ROHM AND HAAS COMPANY (US) 1995-01-17 US claimed
US-5290956-A Graft copolymers for latex ROHM AND HAAS COMPANY (US) 1994-03-01 US claimed
US-11884701-B2 Chromatography membranes, devices containing them, and methods of use thereof MERCK MILLIPORE LTD. (IE) 2024-01-30 US disclosed
EP-3427815-B1 DEVICE WITH LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY MERCK MILLIPORE LTD (IE) 2023-12-06 EP disclosed
US-20210206801-A1 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF MERCK MILLIPORE LTD. (IE) 2021-07-08 US disclosed
US-10981949-B2 Chromatography membranes, devices containing them, and methods of use thereof MERCK MILLIPORE LTD. (IE) 2021-04-20 US disclosed
US-10874990-B2 Layered tubular membranes for chromatography, and methods of use thereof MERCK MILLIPORE LTD. (IE) 2020-12-29 US disclosed
US-10800808-B2 Chromatography membranes, devices containing them, and methods of use thereof MERCK MILLIPORE LTD. (IE) 2020-10-13 US disclosed
US-20190201851-A1 LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY, AND METHODS OF USE THEREOF MERCK MILLIPORE LTD. (IE) 2019-07-04 US disclosed
US-20190040099-A1 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF MERCK MILLIPORE LTD. (IE) 2019-02-07 US disclosed
US-10195567-B2 Layered tubular membranes for chromatography, and methods of use thereof NATRIX SEPARATIONS INC. (CA) 2019-02-05 US disclosed
EP-2709749-A2 LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2014-03-26 EP disclosed
US-20120298582-A1 Layered Tubular Membranes for Chromatography, and Methods of Use Thereof NATRIX SEPARATIONS INC. (CA) 2012-11-29 US disclosed
WO-2012158896-A2 LAYERED TUBULAR MEMBRANES FOR CHROMATOGRAPHY, AND METHODS OF USE THEREOF NATRIX SEPARATIONS INC. (CA) 2012-11-22 WO disclosed
EP-2334413-A2 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF Natrix Separations Inc. (CA) 2011-06-22 EP disclosed
WO-2010027955-A2 CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF NATRIX SEPARATIONS INC. (CA) 2010-03-11 WO disclosed
US-20100059443-A1 Chromatography Membranes, Devices Containing Them, and Methods of Use Thereof NATRIX SEPARATIONS INC. (CA) 2010-03-11 US disclosed
US-5382640-A Polymers with pendant thio-acyl groups used as graft polymerization sites when deprotected ROHM AND HAAS COMPANY (US) 1995-01-17 US disclosed
US-5290956-A Graft copolymers for latex ROHM AND HAAS COMPANY (US) 1994-03-01 US disclosed
EP-0542438-A1 Latent thiol monomers ROHM AND HAAS COMPANY (US) 1993-05-19 EP disclosed