Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28380034 | 0.86 | TSHR (0.53) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| Methacrylic Acid SCHEMBL28419338 | 0.86 | TSHR (0.49) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| Methacrylic Acid SCHEMBL7035194 | 0.86 | TSHR (0.44) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL12944731 | 0.86 | TSHR (0.56) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL56403 | 0.85 | TSHR (0.63) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| Methacrylic Acid SCHEMBL9186775 | 0.83 | TSHR (0.40) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL720931 | 0.83 | TSHR (0.58) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| Methacrylic Acid SCHEMBL9249508 | 0.83 | TSHR (0.40) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| Benzene SCHEMBL28110883 | 0.83 | PKM (0.59) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL2320799 | 0.83 | TSHR (0.57) | TSHRPKMSMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164301-A1 | PVC IMPACT MODIFIER OPAQUE HIGH-IMPACT MBS AND PREPARATION METHOD THEREFOR | 山东东临新材料股份有限公司 | 2020-08-20 | — | — | WO | disclosed |