Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 5/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999234 | 1.00 | AHCY (0.71) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL22855722 | 0.91 | AHCY (0.64) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL22855724 | 0.90 | AHCY (0.65) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL24420285 | 0.87 | AHCY (0.59) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL18517663 | 0.86 | AHCY (0.61) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL18387193 | 0.86 | AHCY (0.61) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL16674884 | 0.85 | AHCY (0.60) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL18351583 | 0.85 | AHCY (0.60) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL24807033 | 0.83 | AHCY (1.00) | AHCYADORA2AADORA1ADORA2BPI4KA | |
| SCHEMBL15759273 | 0.83 | AHCY (0.64) | AHCYADORA2AADORA1ADORA2BPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339980-A1 | High Specificity Genome Editing Using Chemically Modified Guide RNAs | AGILENT TECHNOLOGIES, INC. | 2020-10-29 | — | — | US | disclosed |
| US-10767175-B2 | High specificity genome editing using chemically modified guide RNAs | AGILENT TECHNOLOGIES, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20170355985-A1 | High Specificity Genome Editing Using Chemically Modified Guide RNAs | AGILENT TECHNOLOGIES, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170355985-A1 | High Specificity Genome Editing Using Chemically Modified Guide RNAs | AGILENT TECHNOLOGIES, INC. | 2017-12-14 | — | — | US | disclosed |