Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690930 | 1.00 | FPR2 (0.41) | FPR2SCN9ASMN1; SMN2EGFRAURKA | |
| SCHEMBL19700464 | 1.00 | FPR2 (0.41) | FPR2SCN9ASMN1; SMN2EGFRAURKA | |
| SCHEMBL19690969 | 0.86 | ADORA2A (0.51) | FPR2SCN9AADORA2AADORA1 | |
| SCHEMBL19690825 | 0.84 | PDE5A (0.42) | FPR2SCN9ASMN1; SMN2AURKAAURKB | |
| SCHEMBL19708905 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2EGFRAURKAAURKBADORA2A | |
| SCHEMBL19690893 | 0.80 | AURKA (0.47) | SMN1; SMN2AURKAAURKBADORA2AADORA1 | |
| SCHEMBL19687495 | 0.79 | SMN1; SMN2 (0.43) | FPR2SCN9ASMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL19686910 | 0.79 | LRRK2 (0.38) | FPR2SCN9ASMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL19687494 | 0.78 | SMN1; SMN2 (0.42) | FPR2SCN9ASMN1; SMN2ADORA2AADORA1 | |
| SCHEMBL19690919 | 0.76 | TSHR (0.39) | SMN1; SMN2EGFRAURKAAURKBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | CADENT THERAPEUTICS, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | CADENT THERAPEUTICS, INC. | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170355708-A1 | POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNJ2, KCNJ1 | FPR2 4185/4885SCN9A 79/4885SMN1; SMN2 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.