Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11606548 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL10806921 | 0.82 | KDM4E (0.56) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL17339102 | 0.81 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL893233 | 0.79 | ERAP1 (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL17339130 | 0.79 | ERAP1 (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11422962 | 0.78 | KMT2A (0.48) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL7401891 | 0.78 | ERAP1 (0.48) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Bromide SCHEMBL9210341 | 0.72 | ERAP1 (0.45) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL28555637 | 0.71 | KMT2A (0.57) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL17130343 | 0.71 | PKM (0.42) | KMT2AMEN1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017214269-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2017-12-14 | — | — | WO | disclosed |