⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197016 | 1.00 | — | — | |
| SCHEMBL198166 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL28016729 | 0.98 | SLC22A6 (0.55) | — | |
| SCHEMBL6928104 | 0.98 | SLC22A6 (0.55) | — | |
| SCHEMBL6928966 | 0.98 | SLC22A6 (0.55) | — | |
| SCHEMBL6928106 | 0.98 | SLC22A6 (0.55) | — | |
| SCHEMBL6928974 | 0.98 | SLC22A6 (0.55) | — | |
| SCHEMBL1635793 | 0.98 | SLC22A6 (0.55) | — | |
| SCHEMBL17203945 | 0.89 | SLC22A6 (0.50) | — | |
| SCHEMBL4739671 | 0.89 | SLC22A6 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-222753279-U | Esterification reaction kettle for producing R-4-cyano-3-hydroxybutyric acid ethyl ester | 江苏万年长药业有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-116598052-A | Low-voltage-resistant ultraviolet-resistant cable | 祁冬芳 | 2023-08-15 | — | — | CN | claimed |
| CN-115394477-B | Low-voltage-resistant ultraviolet-resistant cable and preparation method thereof | 青海聚智龙线缆科技有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-115894290-A | Preparation method of atorvastatin calcium intermediate (R) - (-) -4-cyano-3-hydroxy ethyl butyrate | 宿迁阿尔法科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115394477-A | Low-voltage-resistant anti-ultraviolet cable and preparation method thereof | 祁冬芳 | 2022-11-25 | — | — | CN | claimed |
| CN-108033899-B | Preparation method of (R) -6-cyano-5-hydroxy-3-carbonyl hexanoate tert-butyl ester | 浙江科技学院 | 2020-04-10 | — | — | CN | claimed |
| EP-3022213-B1 | PROCESS FOR THE PREPARATION OF ROSUVASTATIN CALCIUM AND PREPARATION OF ITS NOVEL INTERMEDIATES | SUVEN LIFE SCIENCES LTD (IN) | 2017-06-21 | — | — | EP | claimed |
| CN-104292252-B | Synthesis technology of 1-ethoxycarbonyl-5-methyl-(3R)-(tert-butyldimethylsilyloxy) glutaric ester | 浙江科技学院 | 2017-01-18 | — | — | CN | claimed |
| CN-105838700-A | Immobilized halohydrin dehalogenase and application thereof | 浙江工业大学 | 2016-08-10 | — | — | CN | claimed |
| CN-102796750-B | The nucleic acid of nitrilase, encoding nitrilase enzyme, and the method preparing and use them | BASF ENZYMES LLC (US) | 2015-09-16 | — | — | CN | claimed |
| EP-1100768-B1 | PROCESS FOR THE PREPARATION OF R-(-)-CARNITINE | SIGMA TAU IND FARMACEUTI (IT) | 2002-10-02 | — | — | EP | claimed |
| EP-1213354-A2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-12 | — | — | EP | claimed |
| US-6316667-B2 | DECYCLIZATION OF 3-HYDROXY-4-BUTYROLACTONE TO ALKYL 4-HALOGEN-3-HYDROXYBUTYRATE BY REACTION WITH ALCOHOL; CYANATION, AMIDATION, CYCLIZATION TO OXAZOLIDONE; HYDROLYSIS, METHYLATION, QUATERNIZATION | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2001-11-13 | — | — | US | claimed |
| US-20010031892-A1 | Process for the preparation of R-(-)-carnitine | SIGMA-TAU INDUSTRIE FARMACUETICHE RIUNITE S.P.A. (IT) | 2001-10-18 | — | — | US | claimed |
| EP-1100768-A2 | PROCESS FOR THE PREPARATION OF R-(-)-CARNITINE | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006532-A2 | PROCESS FOR THE PREPARATION OF R-(-)-CARNITINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-02-10 | — | — | WO | claimed |
| US-5908953-A | Method for producing (R)-4-cyano-3-hydroxybutyric acid lower alkyl ester | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-01 | — | — | US | claimed |
| EP-0573184-B1 | t-Butyl (R)-(-)-4-Cyano-3-hydroxybutyrate and process for its preparation | TAKASAGO PERFUMERY CO LTD (JP) | 1996-03-13 | — | — | EP | claimed |
| US-5430171-A | T-butyl (R)-(-)-4-cyano-3-hydroxybutyrate and process for preparing the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-07-04 | — | — | US | claimed |
| EP-0573184-A1 | t-Butyl (R)-(-)-4-Cyano-3-hydroxybutyrate and process for its preparation | Takasago International Corporation (JP) | 1993-12-08 | — | — | EP | claimed |