SCHEMBL198166

SCHEMBL198166

N#CC[C@H](O)CC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197016 1.00
SCHEMBL197015 1.00
Ammonia Solution, Strong SCHEMBL28016729 0.98 SLC22A6 (0.55)
SCHEMBL6928104 0.98 SLC22A6 (0.55)
SCHEMBL6928966 0.98 SLC22A6 (0.55)
SCHEMBL6928106 0.98 SLC22A6 (0.55)
SCHEMBL6928974 0.98 SLC22A6 (0.55)
SCHEMBL1635793 0.98 SLC22A6 (0.55)
SCHEMBL17203945 0.89 SLC22A6 (0.50)
SCHEMBL4739671 0.89 SLC22A6 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120714706-B Catalyst and preparation method thereof, and synthesis method of (S) -tert-butyldimethylsilyloxy-glutaric acid monoamide 上海贝美医药科技有限公司 2025-11-07 CN disclosed
CN-120714706-A Catalyst and preparation method thereof, and synthesis method of (S) -tert-butyldimethylsilyloxy-glutaric acid monoamide 上海贝美医药科技有限公司 2025-09-30 CN disclosed
US-20240228501-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US disclosed
EP-4293023-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2023-12-20 EP disclosed
CN-117177974-A Imidazole-containing condensed ring derivative, preparation method and medical application thereof 长春金赛药业有限责任公司 2023-12-05 CN disclosed
CN-116904530-A Biological preparation method of atorvastatin calcium intermediate 江苏福瑞康泰药业有限公司 2023-10-20 CN disclosed
CN-116904530-A Biological preparation method of atorvastatin calcium intermediate 江苏福瑞康泰药业有限公司 2023-10-20 CN disclosed
US-9828594-B2 Nitrilases, nucleic acids encoding them and methods for making and using them BASF ENZYMES LLC (US) 2017-11-28 US disclosed
US-9828594-B2 Nitrilases, nucleic acids encoding them and methods for making and using them BASF ENZYMES LLC (US) 2017-11-28 US disclosed
CN-104829644-B A kind of preparation method of (S) tertiary butyl dimethyl Si base glutaric acid list benzyl ester monoamides 浙江新东港药业股份有限公司 2017-11-14 CN disclosed
WO-2003106413-A2 PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF MICHIGAN STATE UNIVERSITY (US) 2003-12-24 WO disclosed
WO-2003097810-A2 NITRILASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM DIVERSA CORPORATION (US) 2003-11-27 WO disclosed
US-20030124698-A1 Which stereoselectively hydrolyze nitrites or cyanohydrins into acids and ammonia DIVERSA CORPORATION 2003-07-03 US disclosed
EP-1309580-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF OPTICALLY PURE (S)-BETA-HYDROXY-GAMMA-BUTYROLACTONE SK Corporation (KR) 2003-05-14 EP disclosed
WO-2003000840-A2 NITRILASES DIVERSA CORPORATION (US) 2003-01-03 WO disclosed
US-6429319-B1 CATALYTIC HYDROGENATION SK CORPORATION (KR) 2002-08-06 US disclosed
US-20020035275-A1 Continuous process for the production of optically pure (S)- beta-hydroxy-gamma-butyrolactone SK HOLDINGS CO., LTD. (KR) 2002-03-21 US disclosed
WO-2002010147-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF OPTICALLY PURE (S)-β-HYDROXY-η-BUTYROLACTONE SK CORPORATION (KR) 2002-02-07 WO disclosed
US-6340767-B1 REACTION OF LITHIUM AMIDE WITH ACETIC ACID ESTER AND HYDROXY PROPIONIC ACID KANEKA CORPORATION (JP) 2002-01-22 US disclosed
EP-1104750-A1 PROCESSES FOR THE PREPARATION OF 5-HYDROXY-3-OXOPENTANOIC ACID DERIVATIVES KANEKA CORPORATION (JP) 2001-06-06 EP disclosed